Description

Citric Acid-13C6 CAS NO 287389-42-8 is a stable isotope-labeled analog of citric acid, where all six carbon atoms are the carbon-13 (13C) isotope. This compound is essential as an internal standard for precise quantitative analysis using mass spectrometry, eliminating matrix effects and ensuring accurate results. It is critically needed by researchers and quality control laboratories in pharmaceutical development, clinical diagnostics, and metabolic flux analysis.

Application

• Quantitative Mass Spectrometry (MS) Internal Standard: Used for the accurate quantification of endogenous citric acid and related metabolites in complex biological samples like plasma, urine, and tissue extracts.
• Metabolic Pathway Tracing (Metabolomics/Fluxomics): Employed in 13C-isotope labeling studies to map and analyze the citric acid (Krebs) cycle and related metabolic networks in cells and organisms.
• Pharmaceutical Bioanalysis: Serves as a critical reference standard in pharmacokinetic and pharmacodynamic studies for drugs affecting metabolic pathways.
• Clinical Diagnostic Assays: Enhances the precision of diagnostic tests for inborn errors of metabolism, such as disorders in mitochondrial function.
• Food & Beverage Authenticity Testing: Acts as an isotopic standard in methods designed to detect adulteration and verify the origin of food products containing citric acid.
• Environmental & Plant Science Research: Used to study carbon fixation, respiration, and stress responses in plants and environmental samples.

Basic Information

Product Name	Citric Acid-13C6
CAS No.	287389-42-8
Molecular Formula	13C6H8O7
Molecular Weight	198.10 g/mol (approx.)
Synonyms	(13C6)-Citric Acid; Citric Acid (13C6); 2-Hydroxy-1,2,3-propanetricarboxylic-13C6 Acid; 3-Carboxy-3-hydroxypentane-1,5-dioic-13C6 Acid; 13C Labeled Citric Acid; 1,2,3-Propanetricarboxylic acid, 2-hydroxy- (13C6); Isotopic Citric Acid Standard; Citric Acid-13C6 Internal Standard
EINECS	Contact for details

Quality Control

Our Citric Acid-13C6 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research and analytical applications. Each batch is characterized by advanced techniques including NMR and LC-MS to confirm isotopic enrichment and chemical identity. Certificates of Analysis (COA) detailing isotopic purity (atom % 13C), chemical purity, and analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.