Description

Dl-3-Hydroxybutyric Acid-1,3-13C2, Sodium Salt is a stable, isotopically labeled sodium salt of the ketone body 3-hydroxybutyric acid, specifically enriched with carbon-13 at the 1 and 3 positions. This compound serves as a critical internal standard and tracer in metabolic research, enabling precise quantification and pathway analysis. It is essential for researchers and manufacturers in the fields of metabolomics, clinical diagnostics, pharmaceutical development, and nutritional science who require high-purity, well-characterized isotopic standards for mass spectrometry and NMR studies.

Application

• Mass Spectrometry Internal Standard: Used for the accurate quantification of endogenous 3-hydroxybutyrate levels in biological samples (plasma, serum, urine) via LC-MS/MS or GC-MS.
• Metabolic Flux Analysis (MFA): Acts as a stable isotope tracer to study ketone body metabolism, fatty acid oxidation, and energy homeostasis in cell cultures, tissues, or animal models.
• Clinical Research & Diagnostics: Facilitates research into metabolic disorders such as diabetic ketoacidosis, inborn errors of metabolism, and starvation states.
• Pharmaceutical Development: Employed in pharmacokinetic and pharmacodynamic studies of drugs targeting metabolic pathways.
• Nutritional Science: Used to investigate the metabolic effects of ketogenic diets, exogenous ketone supplements, and sports nutrition.
• NMR Spectroscopy: Serves as a reference compound for chemical shift assignment and method development in metabolic profiling.

Basic Information

Product Name	Dl-3-Hydroxybutyric Acid-1,3-13C2, Sodium Salt
CAS No.	287389-34-8
Molecular Formula	C4H713C2NaO3
Molecular Weight	~130.08 g/mol (for 13C2 labeled form)
Synonyms	DL-3-Hydroxybutyric acid-1,3-13C2 sodium salt; Sodium DL-3-hydroxybutyrate-1,3-13C2; (±)-3-Hydroxybutyric acid-1,3-13C2 sodium salt; 3-Hydroxybutanoic acid-1,3-13C2 sodium salt; BHB-13C2 sodium salt; Sodium β-hydroxybutyrate-1,3-13C2; Ketone body 13C2 standard
EINECS	Contact for details

Quality Control

Every batch of our isotopically labeled Dl-3-Hydroxybutyric Acid-1,3-13C2, Sodium Salt is produced and tested under stringent quality management protocols to ensure identity, purity, and isotopic enrichment meet the exacting requirements of analytical and research laboratories. We provide comprehensive Certificates of Analysis (COA) that detail specifications including assay, isotopic purity, chemical purity, and absence of specific impurities. Our quality systems support traceability and consistency for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (chemical purity)
Isotopic Purity	≥ 99 atom % 13C (at 1,3 positions)
Water Content (KF)	≤ 2.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.