Description

Linolenic Acid-13C18 is a stable isotope-labeled analog of the essential ω-3 fatty acid, α-linolenic acid (ALA), where all 18 carbon atoms are the carbon-13 isotope. This compound is a critical tool for advanced analytical research, enabling precise metabolic pathway tracing and quantitative analysis in complex biological systems. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, nutritional science, and clinical diagnostics sectors for applications requiring high specificity and accuracy.

Application

• Isotope Dilution Mass Spectrometry (IDMS): Serves as an internal standard for the accurate quantification of endogenous linolenic acid and its metabolites in biological fluids and tissues.
• Metabolic Flux Analysis: Used to trace and model the metabolic pathways of ω-3 fatty acids in nutritional, pharmacological, and biochemical studies.
• Clinical Research: Enables precise measurement of fatty acid uptake, distribution, and conversion in human and animal studies related to cardiovascular health and inflammation.
• Pharmaceutical Development: Supports drug metabolism and pharmacokinetic (DMPK) studies for lipid-based therapeutics and nutraceuticals.
• Food & Nutritional Science: Employed in the analysis of fortified foods, dietary supplements, and infant formula to ensure accurate labeling and study bioavailability.
• Environmental & Plant Science: Facilitates research into lipid biosynthesis and metabolism in plants and microorganisms.

Basic Information

Product Name	Linolenic Acid-13C18
CAS No.	287111-28-8
Molecular Formula	13C18H30O2
Molecular Weight	~294.4 g/mol
Synonyms	(9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid-13C18; α-Linolenic acid-13C18; ALA-13C18; 9,12,15-Octadecatrienoic acid-13C18, (Z,Z,Z)-; Linolenic Acid (all carbon-13); 13C18-Linolenic acid; ω-3 fatty acid-13C18
EINECS	Contact for details

Quality Control

Our Linolenic Acid-13C18 is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of analytical research. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity by HPLC, and identity confirmation by spectroscopic methods. We adhere to a quality management system to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. For long-term storage, solutions should be prepared in appropriate, degassed solvents and kept frozen. Allow the sealed vial to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR / NMR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98%
Solubility	Soluble in ethanol, DMSO, chloroform; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.