Description

Palmitic Acid-1,2,3,4-13C4 is a stable isotope-labeled analog of palmitic acid, where four carbon atoms at the 1, 2, 3, and 4 positions are enriched with the carbon-13 isotope. This compound is essential as an internal standard for precise quantitative analysis in mass spectrometry-based metabolomic and lipidomic studies. It is primarily used by researchers and analytical laboratories in pharmaceutical development, nutritional science, and clinical diagnostics to ensure accurate measurement of palmitic acid and related metabolic pathways. The product is supplied under strict quality control to guarantee isotopic purity and chemical stability for sensitive applications.

Application

• Internal Standard for Quantitative Mass Spectrometry (MS): Used as a critical reference compound in LC-MS and GC-MS workflows for the absolute quantification of endogenous palmitic acid and its derivatives in complex biological matrices.
• Metabolic Flux Analysis: Enables the tracing of carbon atoms through metabolic pathways, such as fatty acid synthesis and β-oxidation, in cell culture and in vivo studies.
• Clinical Research & Diagnostics: Facilitates the accurate measurement of palmitic acid levels in plasma, serum, and tissue samples for studies related to metabolic disorders, cardiovascular health, and diabetes.
• Pharmaceutical R&D: Supports drug discovery and development efforts focused on lipid metabolism, serving as a tracer in pharmacokinetic and pharmacodynamic studies.
• Nutritional Science: Employed in research investigating dietary fat absorption, metabolism, and the impact of specific nutrients on lipid profiles.
• Biomarker Discovery & Validation: Acts as a stable isotope-labeled standard in targeted metabolomics panels to identify and validate lipid-based biomarkers for disease.

Basic Information

Item	Detail
Product Name	Palmitic Acid-1,2,3,4-13C4
CAS No.	287100-89-4
Molecular Formula	¹³C₄H₃₂O₂
Molecular Weight	Contact for details
Synonyms	Hexadecanoic-1,2,3,4-13C4 Acid; [1,2,3,4-13C4]Palmitic Acid; 13C Labeled Palmitic Acid; Isotopically Labeled Palmitate; C16:0-1,2,3,4-13C4; 1,2,3,4-Tetradeutero-palmitic Acid (common misnomer); FA 16:0-13C4
EINECS	Contact for details

Quality Control

Every batch of Palmitic Acid-1,2,3,4-13C4 is manufactured and analyzed under a strict quality management system. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and Mass Spectrometry to confirm isotopic enrichment and positional labeling. Certificates of Analysis (COA) are provided with each shipment, detailing the assay, isotopic purity, and solvent content. Our quality commitment ensures reliability for your most sensitive research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. Under these conditions, the product is stable for extended periods. The material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Isotopic Purity (13C)	≥ 99 atom % 13C
Isotopic Enrichment (Positional)	≥ 98% at 1,2,3,4-positions
Chemical Purity (HPLC)	≥ 98%
Solvent Content (Residual)	< 0.5% (by NMR)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.