Description

D-Glucitol-2-13C CAS NO 287100-73-6 is a stable isotope-labeled analog of D-glucitol (sorbitol), specifically enriched with carbon-13 at the second carbon position. This compound is essential for advanced research and analytical applications requiring precise metabolic pathway tracing and quantification. It is primarily utilized by pharmaceutical, biotechnology, and academic research institutions engaged in metabolic studies, drug development, and stable isotope labeling mass spectrometry (SILMS).

Application

• Metabolic Flux Analysis (MFA): Used as a labeled tracer to study carbohydrate metabolism and glycolytic pathways in cell cultures and biological systems.
• Pharmaceutical Research: Serves as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of sorbitol and related metabolites in drug metabolism and pharmacokinetics (DMPK) studies.
• Nutritional Science: Employed in research investigating sugar alcohol metabolism, glycemic response, and the development of specialized nutritional products.
• Biochemical Research: A critical tool for enzymology studies, helping to elucidate the mechanisms of enzymes like aldose reductase and sorbitol dehydrogenase.
• Diagnostic Development: Used in the formulation and calibration of diagnostic assays for conditions like diabetes, where sorbitol pathway activity is a key biomarker.

Basic Information

Product Name	D-Glucitol-2-13C
CAS No.	287100-73-6
Molecular Formula	C513CH14O6
Molecular Weight	183.15 g/mol (for 13C1 labeled)
Synonyms	Sorbitol-2-13C; D-Sorbitol-2-13C; (2S,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol-2-13C; Glucitol-2-13C; L-Gulitol-2-13C; Isotopic Sorbitol; Carbon-13 Labeled Sorbitol; 13C1-Sorbitol
EINECS	Contact for details

Quality Control

Our D-Glucitol-2-13C is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) are provided, detailing specifications for isotopic purity (atom % 13C), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We support research and compliance needs for GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or under an inert atmosphere to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (chemical purity)
Isotopic Purity	≥ 99 atom % 13C at C-2
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.