Description

D-[2-13C]Mannitol is a stable isotope-labeled analog of the sugar alcohol mannitol, specifically enriched with carbon-13 at the 2-position. This compound is an essential tool in advanced research, enabling precise metabolic pathway tracing and quantification using techniques like Nuclear Magnetic Resonance (NMR) spectroscopy and Mass Spectrometry (MS). It is primarily utilized by researchers and scientists in the pharmaceutical, biotechnology, and academic sectors for drug metabolism studies, biomarker discovery, and detailed biochemical analysis.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to map and quantify intracellular metabolic pathways in cell cultures and microorganisms.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as an internal standard for the accurate quantification of mannitol and related compounds in bioanalytical assays.
• Biomedical Research: Enables non-invasive investigation of metabolic disorders, cancer metabolism, and other physiological processes in model systems.
• NMR Spectroscopy Standard: Acts as a chemical shift reference and calibration standard in complex mixture analysis.
• Stable Isotope Labeling: A key precursor for the synthesis of more complex labeled compounds for specialized research applications.

Basic Information

Product Name	D-[2-13C]Mannitol
CAS No.	287100-69-0
Molecular Formula	C613CH14O6
Molecular Weight	183.15 g/mol (for 13C1 isotopologue)
Synonyms	(2-13C)Mannitol; D-Mannitol-2-13C; [2-13C]-D-Mannitol; 1,2,3,4,5,6-Hexanehexol-2-13C; (2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol-2-13C; Mannitol-2-13C; Isotopic Mannitol
EINECS	Contact for details

Quality Control

Every batch of D-[2-13C]Mannitol is produced and analyzed under strict quality protocols to ensure the highest isotopic and chemical purity for research applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (Atom % 13C), chemical purity, and specific analytical results. Our quality commitment aligns with the stringent requirements of analytical and pharmaceutical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.