Description

Sodium Butyrate-1,2-13C2 is a stable isotope-labeled derivative of sodium butyrate, where the first two carbon atoms are enriched with the 13C isotope. This compound is essential for advanced research requiring precise metabolic and pharmacokinetic tracing, offering unparalleled accuracy in mass spectrometry and NMR studies. It is a critical reagent for scientists in pharmaceutical development, nutritional biochemistry, and metabolic research who require high-purity, isotopically labeled standards for quantitative analysis.

Application

• Stable Isotope-Labeled Internal Standards: For precise quantification of butyrate and related metabolites in complex biological matrices using GC-MS or LC-MS.
• Metabolic Pathway Tracing: To investigate the fate of short-chain fatty acids (SCFAs) in in vitro and in vivo studies, including gut microbiome research.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: As a tracer to study the absorption, distribution, metabolism, and excretion (ADME) of butyrate-based therapeutics.
• Nutritional and Biochemical Research: For exploring the role of butyrate in cellular signaling, energy metabolism, and epigenetic regulation (e.g., histone deacetylase inhibition).
• Diagnostic Assay Development: Used in calibrators and controls for clinical diagnostic tests measuring SCFA levels.

Basic Information

Product Name	Sodium Butyrate-1,2-13C2
CAS No.	286367-74-6
Molecular Formula	13C2H7NaO2
Molecular Weight	114.06 (for 13C2 labeled form)
Synonyms	Butanoic-1,2-13C2 acid, sodium salt; Sodium 1,2-13C2-butanoate; 13C2-Sodium butyrate; [1,2-13C2]-Sodium butyrate; Labeled sodium butyrate; Isotopic sodium butyrate; Na-13C2-butyrate
EINECS	Contact for details

Quality Control

Every batch of Sodium Butyrate-1,2-13C2 is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment (by NMR and/or MS), and identification. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C (1,2-positions)
Chemical Purity	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.