Description

3-Phenylpropionic Acid-2,3-13C2 is a stable isotope-labeled analog of hydrocinnamic acid, specifically enriched with carbon-13 at the 2 and 3 positions of the propionic acid chain. This precise isotopic labeling is critical for applications requiring high sensitivity and specificity in analytical detection and metabolic pathway tracing. It is an essential research-grade material for scientists and quality control professionals in the pharmaceutical, agrochemical, and life science industries engaged in advanced analytical method development.

Application

• As an internal standard for the precise quantification of hydrocinnamic acid and related compounds in complex biological matrices using Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS).
• A key tracer molecule in metabolic flux analysis and pharmacokinetic studies to elucidate the absorption, distribution, metabolism, and excretion (ADME) profiles of drug candidates and natural products.
• Used in the synthesis of more complex isotope-labeled intermediates for pharmaceutical research and development, enabling the creation of labeled active pharmaceutical ingredients (APIs).
• Essential for developing and validating regulatory-compliant analytical methods in compliance with guidelines from agencies like the FDA and EMA.
• Applied in environmental analysis to trace the degradation pathways of related aromatic compounds.
• Utilized in nutritional and food science research to study the metabolism of phenylpropanoic acids derived from the diet.

Basic Information

Product Name	3-Phenylpropionic Acid-2,3-13C2
CAS No.	286367-71-3
Molecular Formula	C7H813C2O2
Molecular Weight	~166.17 g/mol (for 13C2 labeled form)
Synonyms	Hydrocinnamic Acid-2,3-13C2; 3-Phenylpropanoic Acid-2,3-13C2; (2,3-13C2)Benzenepropanoic Acid; β-Phenylpropionic Acid-2,3-13C2; 2,3-13C2-Dihydrocinnamic Acid; 3-Phenyl-1-13C-propionic-2-13C Acid; Phenylpropionic Acid-2,3-13C2; Isotope Labeled Hydrocinnamic Acid
EINECS	Contact for details

Quality Control

Every batch of our 3-Phenylpropionic Acid-2,3-13C2 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with specifications typically including isotopic enrichment (atom % 13C), chemical purity by HPLC, and identity confirmation by NMR and MS. Certificates of Analysis (COA) detailing all relevant parameters are provided to ensure traceability and compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the container under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure and labeling pattern
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C at positions 2 & 3
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.