Description

Sodium Butyrate-2,4-13C2 is a stable isotope-labeled derivative of sodium butyrate, specifically enriched with carbon-13 at the 2 and 4 positions. This precise labeling makes it an indispensable internal standard and tracer for advanced analytical and metabolic research. It is primarily utilized by research institutions and pharmaceutical companies engaged in mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and metabolic pathway studies. The compound provides critical data integrity for quantitative analysis in complex biological matrices.

Application

• Stable Isotope-Labeled Internal Standard for accurate quantification in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS).
• Metabolic Tracer in biomedical and nutritional research to study short-chain fatty acid (SCFA) metabolism, gut microbiome function, and energy homeostasis.
• NMR Spectroscopy studies, leveraging the 13C enrichment for detailed structural and dynamic analysis of metabolic processes.
• Pharmaceutical R&D for drug metabolism and pharmacokinetics (DMPK) studies, especially for compounds targeting histone deacetylase (HDAC) inhibition.
• Biochemical Research tool for investigating the role of butyrate in cell signaling, inflammation, and epigenetics.
• Quality Control Reference Material for analytical laboratories requiring high-purity certified standards.

Basic Information

Product Name	Sodium Butyrate-2,4-13C2
CAS No.	286367-68-8
Molecular Formula	C413C2H7NaO2
Molecular Weight	114.08 (for 13C2 labeled form)
Synonyms	Butyric-2,4-13C2 acid sodium salt; Sodium [2,4-13C2]butyrate; [13C2]-Sodium butyrate; 13C Labeled Sodium Butyrate; Sodium Butanoate-2,4-13C2; NaB-13C2; Isotopically Labeled Sodium Butyrate
EINECS	Contact for details

Quality Control

Every batch of Sodium Butyrate-2,4-13C2 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, verified by advanced spectroscopic and chromatographic methods including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing assay, isotopic enrichment, and impurity profiles to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or under an inert atmosphere to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C (at positions 2 & 4)
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.