Description

Dimethyl Sulfate (13C2) is a stable isotope-labeled analog of dimethyl sulfate, where both methyl groups are enriched with carbon-13. This compound is a critical reagent for advanced analytical chemistry and metabolic research, providing a non-radioactive, highly sensitive tracer for precise quantification and pathway elucidation. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental science sectors who require high-fidelity internal standards for mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a quantitative reference standard in GC-MS and LC-MS analyses for detecting and quantifying unlabeled dimethyl sulfate or related compounds.
• Metabolic Pathway Tracing: Used in stable isotope labeling experiments (SIL) to study methylation pathways and the metabolic fate of chemicals in biological systems.
• NMR Spectroscopy: Provides a distinct spectroscopic signature for structural analysis and reaction mechanism studies in organic and medicinal chemistry.
• Pharmaceutical Impurity Profiling: Aids in the identification and accurate measurement of genotoxic impurities (GTIs) like dimethyl sulfate in active pharmaceutical ingredients (APIs).
• Environmental Analysis: Employed as a tracer in method development for detecting alkylating agents in air, water, and soil samples.
• Chemical Synthesis Research: Acts as a labeled methylating agent to track the incorporation of methyl groups in synthesized molecules.

Basic Information

Product Name	Dimethyl Sulfate (13C2)
CAS No.	286013-18-1
Molecular Formula	(13C)2H6O4S
Molecular Weight	~128.10 g/mol (13C enriched)
Synonyms	DMS-(13C2); [13C2]-Dimethyl Sulfate; Sulfuric Acid, Dimethyl Ester (13C2); (13C)Methyl Sulfate; Isotopically Labeled Dimethyl Sulfate; [13C2]DMS; 13C-Labeled Dimethyl Sulfate; Methyl Sulfate (13C2)
EINECS	Contact for details

Quality Control

Every batch of our Dimethyl Sulfate (13C2) is manufactured and analyzed under strict quality systems to ensure exceptional isotopic purity and chemical integrity, suitable for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity, and specific impurity profiles. Our quality commitment aligns with the rigorous standards expected in analytical and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Purity (13C)	≥99 atom %
Chemical Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.