Description

Stat5 Inhibitor CAS NO 285986-31-4 is a potent and selective small molecule inhibitor of the Signal Transducer and Activator of Transcription 5 (STAT5) protein. This compound matters for researchers and developers targeting the JAK-STAT signaling pathway, a critical mediator in cellular processes like proliferation, differentiation, and apoptosis. It is primarily needed by pharmaceutical R&D teams, academic institutions, and biotechnology companies focused on oncology, immunology, and inflammatory disease research.

Application

• Biomedical Research: A key tool compound for studying the role of STAT5 in signal transduction pathways and cellular function.
• Oncology Target Validation: Used in vitro and in vivo to investigate and validate STAT5 as a therapeutic target in various cancers, including leukemias and solid tumors.
• Drug Discovery & Development: Serves as a lead compound or reference standard in high-throughput screening and structure-activity relationship (SAR) studies for novel STAT5 inhibitors.
• Immunology Studies: Employed to dissect the function of STAT5 in immune cell development, differentiation, and cytokine signaling.
• Mechanistic Biology: Facilitates the elucidation of disease mechanisms where constitutive STAT5 activation is implicated.

Basic Information

Product Name	Stat5 Inhibitor CAS NO 285986-31-4
CAS No.	285986-31-4
Molecular Formula	C₂₀H₂₀N₄O₂
Molecular Weight	348.40 g/mol
Synonyms	STAT5 Inhibitor; NSC 74859; S31-201; 2-[(4-{[4-(4-Methylpiperazin-1-yl)phenyl]amino}quinazolin-2-yl)thio]ethanol; 2-({4-[(4-Methyl-1-piperazinyl)phenyl]amino}-2-quinazolinyl)thio)ethanol; 2-({4-[(4-Methylpiperazin-1-yl)phenyl]amino}quinazolin-2-yl)sulfanyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our Stat5 Inhibitor is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.