Description

Guanosine-13C10, 15N5 5'-Triphosphate Sodium Salt 99 Atom %13C 99 Atom%15N is a high-purity, isotopically labeled nucleotide essential for advanced analytical and diagnostic research. This compound is critical for applications requiring precise metabolic tracing and quantification due to its high isotopic enrichment of 99 atom % for both 13C and 15N. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers engaged in metabolomics, drug development, and biomarker discovery. The product, identified by CAS NO 285978-17-8, offers exceptional isotopic purity for reliable and reproducible experimental results.

Application

• Metabolomics & Stable Isotope-Resolved Metabolomics (SIRM): As a highly enriched tracer for studying purine metabolism, nucleotide synthesis, and cellular energy pathways.
• Pharmaceutical R&D: For investigating the mechanism of action, metabolic fate, and potential toxicity of nucleoside analog drugs.
• Diagnostic Assay Development: Serving as a critical internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and LC-MS/MS methods for accurate quantification of guanosine nucleotides in biological samples.
• Biochemical Research: Used in enzymatic studies, RNA synthesis research, and as a substrate for studying GTP-binding proteins (G-proteins) and kinases.
• Nutritional Science: For tracing nucleotide metabolism and turnover in nutritional studies.

Basic Information

Product Name	Guanosine-13C10, 15N5 5'-Triphosphate Sodium Salt 99 Atom %13C 99 Atom%15N
CAS No.	285978-17-8
Molecular Formula	C1013C10H12N515N5O14P3Nax (x≈4)
Molecular Weight	~587.1 (for free acid, unlabeled C10H16N5O14P3) Contact for exact labeled sodium salt MW.
Synonyms	13C10,15N5-GTP Sodium Salt; Guanosine-5'-triphosphate-13C10,15N5 sodium salt; [13C10,15N5]-GTP; Isotopically Labeled GTP; (13C10,15N5)GTP; GTP-13C10,15N5; 13C10 15N5 Guanosine triphosphate sodium; 99% 13C10 99% 15N5 GTP
EINECS	Contact for details

Quality Control

Every batch of our isotopically labeled nucleotides is produced and tested to meet the stringent requirements of research and diagnostic applications. Certificates of Analysis (COA) are provided, detailing key parameters such as isotopic purity (Atom % 13C and 15N), chemical purity (by HPLC), and identity confirmation (by NMR and MS). Our quality system ensures reproducible performance and traceability for your critical research. Specifications are aligned with the needs of analytical reference standard production.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR/MS)	Conforms to structure
Isotopic Purity (Atom % 13C)	≥ 99%
Isotopic Purity (Atom % 15N)	≥ 99%
Chemical Purity (HPLC)	≥ 95%
pH (in solution)	6.0 - 8.0
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.