Description

L-Alanine-2-13C-15N is a stable isotope-labeled analog of the essential amino acid L-alanine, specifically enriched with carbon-13 at the 2-position and nitrogen-15. This high-purity labeled compound is critical for advanced research requiring precise metabolic pathway tracing and quantitative analysis. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and academic research sectors for applications in nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), and metabolic flux analysis.

Application

• Metabolic Research & Flux Analysis: Used as a tracer to study amino acid metabolism, protein synthesis, and gluconeogenesis pathways in cell cultures, tissues, and whole organisms.
• Quantitative Proteomics & Biomarker Discovery: Serves as an internal standard in mass spectrometry for the accurate quantification of proteins and peptides.
• NMR Spectroscopy Studies: Provides a non-radioactive, stable isotopic label for structural and dynamic studies of biomolecules and metabolic intermediates.
• Pharmaceutical Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug compounds and their metabolites.
• Nutritional Science Research: Used to investigate protein turnover, amino acid requirements, and metabolic responses in nutritional studies.
• Manufacturing of Labeled Compounds: Acts as a high-purity building block for the synthesis of more complex isotopically labeled peptides, proteins, or pharmaceuticals.

Basic Information

Product Name	L-Alanine-2-13C-15N
CAS No.	285977-86-8
Molecular Formula	C3H713CNO2
Molecular Weight	91.07 g/mol (for 13C1, 15N1 labeled form)
Synonyms	(2S)-2-Azanylpropanoic-2-13C-15N acid; L-α-Alanine-2-13C,15N; (S)-Alanine-2-13C,15N; Alanine-2-13C,15N; L-Alanine-2-13C,15N; [2-13C,15N]-L-Alanine; Stable Isotope Labeled L-Alanine
EINECS	Contact for details

Quality Control

Our L-Alanine-2-13C-15N is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity for sensitive research applications. Each batch is analyzed to confirm identity, isotopic enrichment, and purity, with comprehensive Certificates of Analysis (COA) provided. We adhere to relevant industry standards for fine chemicals and can support compliance needs for research under GLP (Good Laboratory Practice) guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (Chemical Purity)
Isotopic Enrichment	≥ 99 atom % 13C; ≥ 98 atom % 15N
Optical Rotation	[α]D20: +13.5° to +15.5° (c=1 in H2O)
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.