Description

4-Fluorobenzoic Acid-α-13C-2,3,5,6-D4 is a stable isotope-labeled derivative of 4-fluorobenzoic acid, specifically enriched with carbon-13 at the alpha position and deuterium at the 2, 3, 5, and 6 positions of the aromatic ring. This compound is an essential internal standard and tracer in quantitative mass spectrometry, enabling precise and accurate analysis in complex matrices. It is primarily utilized by researchers and analytical laboratories in the pharmaceutical, agrochemical, and environmental science sectors for method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS: Used as a high-purity, non-interfering internal standard for the quantitative analysis of 4-fluorobenzoic acid and related compounds in bioanalytical assays.
• Metabolite Tracing in Drug Development: Serves as a stable isotope tracer to study the metabolic pathways, absorption, and excretion of fluorinated pharmaceutical compounds.
• Environmental Fate Studies: Employed in research to track the degradation, transformation, and movement of fluorinated aromatic pollutants in environmental samples.
• NMR Spectroscopy: Acts as a valuable probe in nuclear magnetic resonance (NMR) studies due to its distinct isotopic signature, aiding in structural elucidation and mechanistic investigations.
• Quality Control & Method Validation: Critical for validating analytical methods, ensuring accuracy, precision, and compliance with regulatory standards in GLP/GMP environments.

Basic Information

Product Name	4-Fluorobenzoic Acid-α-13C-2,3,5,6-D4
CAS No.	285977-82-4
Molecular Formula	C6D4F13COOH
Molecular Weight	Contact for details
Synonyms	4-Fluoro[α-13C,2,3,5,6-D4]benzoic Acid; [13C1,D4]-4-Fluorobenzoic Acid; Benzoic-α-13C-2,3,5,6-D4 acid, 4-fluoro-; 4-Fluorobenzoic Acid (13C1, D4); p-Fluorobenzoic Acid-α-13C-2,3,5,6-D4; 4-FBA-13C,D4; Isotopically Labeled 4-Fluorobenzoic Acid
EINECS	Contact for details

Quality Control

Every batch of our 4-Fluorobenzoic Acid-α-13C-2,3,5,6-D4 is produced and tested under strict quality management systems. We ensure high chemical purity and isotopic enrichment as specified, supported by comprehensive analytical data from NMR, MS, and HPLC. Certificates of Analysis (COA) detailing purity, isotopic abundance, and impurity profiles are provided with each shipment to guarantee traceability and compliance with your research or quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98% (Chemical Purity)
Isotopic Enrichment	≥99 atom % 13C; ≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.