Description

1-Phenylethanol-1,2-13C2 is a stable isotope-labeled analog of 1-phenylethanol, where the carbon atoms at positions 1 and 2 are enriched with the 13C isotope. This compound is essential for applications requiring precise internal standards for quantitative analysis, enabling accurate measurement and traceability in complex matrices. It is primarily utilized by researchers and analytical laboratories in the pharmaceutical, agrochemical, and metabolomics fields for advanced mass spectrometry (MS), nuclear magnetic resonance (NMR) spectroscopy, and metabolic pathway studies.

Application

• Quantitative Mass Spectrometry (MS): Serves as a critical internal standard for the accurate quantification of 1-phenylethanol and related compounds in LC-MS and GC-MS analyses, correcting for instrument variability and matrix effects.
• Metabolic Flux Analysis: Used as a labeled tracer to study and map metabolic pathways in biological systems, providing insights into cellular processes and drug metabolism.
• NMR Spectroscopy: Acts as a reference standard in 13C NMR studies due to its specific isotopic enrichment, aiding in structural elucidation and method development.
• Pharmaceutical Research: Employed in drug development and pharmacokinetic studies to ensure precise measurement of active pharmaceutical ingredients (APIs) and their metabolites.
• Forensic and Environmental Analysis: Enhances the accuracy and reliability of trace-level detection for phenylethanol derivatives in forensic toxicology and environmental monitoring.
• Quality Control & Method Validation: Provides a certified reference material for validating analytical methods, ensuring compliance with regulatory standards like GLP and ISO 17025.

Basic Information

Product Name	1-Phenylethanol-1,2-13C2
CAS No.	285138-87-6
Molecular Formula	C8H10O (with 13C at positions 1 & 2)
Molecular Weight	124.15 g/mol (for 13C2 labeled form)
Synonyms	(±)-1-Phenylethanol-1,2-13C2; (RS)-1-Phenylethanol-1,2-13C2; α-Methylbenzyl Alcohol-1,2-13C2; 1-Phenylethyl Alcohol-1,2-13C2; Methylphenylcarbinol-1,2-13C2; Styralyl Alcohol-1,2-13C2; sec-Phenethyl Alcohol-1,2-13C2; 13C Labeled 1-Phenylethanol
EINECS	Contact for details

Quality Control

Every batch of 1-Phenylethanol-1,2-13C2 undergoes rigorous analytical testing to ensure the highest standards of isotopic purity and chemical identity. Our quality assurance protocols are designed to meet the stringent requirements of research and analytical applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as isotopic enrichment, chemical purity, and spectroscopic confirmation. We support compliance with relevant quality frameworks, including GMP where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and potential concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C at positions 1 & 2
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.