Description

3,4,5-Trifluorotoluene is a high-purity fluorinated aromatic building block essential for advanced chemical synthesis. This compound is valued for its trifluoromethyl and fluorine substituents, which impart unique electronic and steric properties critical for modifying molecular interactions. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to desired electronic properties and performance stability.
• Polymer & Resin Modifier: Employed to introduce fluorine into polymer chains, enhancing material properties such as chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis Reagent: Acts as a versatile reagent in cross-coupling reactions and other organic transformations to construct complex fluorinated molecules for research and development.

Basic Information

Product Name	3,4,5-Trifluorotoluene
CAS No.	284463-96-3
Molecular Formula	C7H5F3
Molecular Weight	146.11 g/mol
Synonyms	1,2,3-Trifluoro-5-methylbenzene; 3,4,5-Trifluoromethylbenzene; Toluene, 3,4,5-trifluoro-; α,α,α-Trifluoro-3,4,5-trimethyltoluene (incorrect but common misnomer); 3,4,5-Trifluoro-1-methylbenzene; Benzene, 1-methyl-3,4,5-trifluoro-
EINECS	Contact for details

Quality Control

Our 3,4,5-Trifluorotoluene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizing agents. Recommended storage temperature is 2-25°C. The container should be kept tightly sealed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.