Description

4-(4,4,4-Trifluoro-Butoxy)-Benzaldehyde is a high-value fluorinated aromatic aldehyde building block, distinguished by its trifluorobutoxy side chain which imparts unique electronic and lipophilic properties. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine moiety improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting materials.
• Polymer & Resin Modifier: Incorporated to alter the surface energy, chemical resistance, and optical properties of high-performance polymers.
• Organic Ligand Synthesis: Used to prepare specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A versatile building block for methodological studies and exploratory chemistry in fluoroorganic compounds.

Basic Information

Product Name	4-(4,4,4-Trifluoro-Butoxy)-Benzaldehyde
CAS No.	280776-44-5
Molecular Formula	C11H11F3O2
Molecular Weight	232.20 g/mol
Synonyms	4-(4,4,4-Trifluorobutoxy)benzaldehyde; p-(4,4,4-Trifluorobutoxy)benzaldehyde; Benzaldehyde, 4-(4,4,4-trifluorobutoxy)-; 4-(4,4,4-Trifluorobutoxy)benzaldehyde (CAS 280776-44-5); 4-(4,4,4-Trifluorobutoxy)benzenecarbaldehyde; 4-(3,3,3-Trifluoropropoxymethyl)benzaldehyde (related isomer); TFBOB (common abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 4-(4,4,4-Trifluoro-Butoxy)-Benzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.