Description

Sb216763 is a potent and selective small molecule inhibitor with significant research and development applications. This compound is valued for its high purity and consistent performance in critical biochemical pathways. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for target validation, mechanism-of-action studies, and early-stage drug discovery programs.

Application

• Pharmaceutical Research: Used as a key chemical tool for studying specific kinase-related pathways and validating novel therapeutic targets.
• Biochemical Assay Development: Serves as a reference standard or active control in high-throughput screening (HTS) and in vitro assay systems.
• Preclinical Studies: Employed in cellular and animal models to investigate disease mechanisms and evaluate potential efficacy.
• Chemical Biology: Acts as a probe to elucidate protein function and understand complex signaling networks within cells.
• Academic Research: Supports fundamental scientific investigations in universities and research institutes focused on molecular biology and medicinal chemistry.
• Biotech R&D: Integral to discovery pipelines for developing new molecular entities and optimizing lead compounds.

Basic Information

Product Name	Sb216763
CAS No.	280744-09-4
Molecular Formula	C16H12BrN3O2S
Molecular Weight	390.26 g/mol
Synonyms	3-(3-Chloro-4-hydroxyphenylamino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione; SB-216763; GSK-3 Inhibitor IX; 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione; Glycogen Synthase Kinase-3β Inhibitor; ATP-competitive GSK-3 Inhibitor
EINECS	Contact for details

Quality Control

Our Sb216763 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research purposes. Each lot undergoes comprehensive analytical testing, including HPLC for purity confirmation and identity verification by spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.