Description

3-Acetyl-2-(4-Fluorophenyl)-Pyridine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both acetyl and fluorophenyl substituents, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and liquid crystals with specific optical or electronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a scaffold for constructing more complex heterocyclic compounds in medicinal chemistry.

Basic Information

Product Name	3-Acetyl-2-(4-Fluorophenyl)-Pyridine
CAS No.	280573-47-9
Molecular Formula	C13H10FNO
Molecular Weight	215.22 g/mol
Synonyms	1-[2-(4-Fluorophenyl)pyridin-3-yl]ethanone; 3-Acetyl-2-(p-fluorophenyl)pyridine; 2-(4-Fluorophenyl)-3-acetylpyridine; Ethanone, 1-[2-(4-fluorophenyl)-3-pyridinyl]-; 280573-47-9
EINECS	Contact for details

Quality Control

Our 3-Acetyl-2-(4-Fluorophenyl)-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.