Description

Benzeneethanimidamide,n-Hydroxy-4-(Trifluoromethoxy)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethoxy-substituted amidoxime structure. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing next-generation small molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, leveraging the trifluoromethoxy group for improved activity and environmental profile.
• Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and functionalized aromatic systems in medicinal chemistry.
• Material Science: Potential monomer or additive in the research of specialty polymers with specific optical or electronic properties.
• Bioconjugation & Probe Development: Utilized in biochemical research for creating labeled probes or affinity ligands due to its reactive amidoxime functional group.

Basic Information

Product Name	Benzeneethanimidamide,n-Hydroxy-4-(Trifluoromethoxy)-
CAS No.	280110-83-0
Molecular Formula	C9H9F3N2O2
Molecular Weight	234.18 g/mol
Synonyms	4-(Trifluoromethoxy)benzamidoxime; N-Hydroxy-4-(trifluoromethoxy)benzenecarboximidamide; p-(Trifluoromethoxy)benzamidoxime; 4-Trifluoromethoxybenzamidoxime; Benzamidoxime, 4-(trifluoromethoxy)-; 1-[4-(Trifluoromethoxy)phenyl]methanimidamide, N-hydroxy-; Amidoxime, 4-(trifluoromethoxy)benz-
EINECS	Contact for details

Quality Control

Our production of Benzeneethanimidamide,n-Hydroxy-4-(Trifluoromethoxy)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.