Description

9,11-Dioxo-15S-Hydroxy-Prosta-5Z,13E-Dien-1-Oic Acid CAS NO 275816-51-8 is a high-purity prostaglandin derivative, a key synthetic intermediate in advanced pharmaceutical research and development. Its precise stereochemistry and functional groups make it an invaluable building block for the synthesis of bioactive lipid mediators and novel therapeutic agents. This compound is primarily utilized by research institutions and pharmaceutical companies focused on inflammation, immunology, and metabolic pathway studies.

Application

• Pharmaceutical Intermediate: Critical precursor in the multi-step synthesis of prostaglandin-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound for studying eicosanoid signaling pathways, receptor binding, and enzyme activity assays.
• Medicinal Chemistry: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities targeting inflammatory diseases.
• Analytical Standard: Employed in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) for method development, validation, and quality control of related compounds.
• Academic Research: Facilitates fundamental research in lipidomics, cell biology, and the molecular mechanisms of pain and fever.

Basic Information

Product Name	9,11-Dioxo-15S-Hydroxy-Prosta-5Z,13E-Dien-1-Oic Acid
CAS No.	275816-51-8
Molecular Formula	C₂₀H₂₈O₆
Molecular Weight	364.44 g/mol
Synonyms	15(S)-Hydroxy-9,11-dioxoprosta-5Z,13E-dien-1-oic Acid; 15S-Hydroxy-9,11-dioxo-prosta-5Z,13E-dien-1-oic Acid; 9,11-Diketo-15S-hydroxy-prosta-5Z,13E-dien-1-oic Acid; PGA₂ Derivative; Prostaglandin A₂ Analog; 15(S)-H-9,11-DK-PGA₂; 275816-51-8; 9,11-Dioxo-15S-Hydroxy-Prosta-5Z,13E-Dienoic Acid
EINECS	Contact for details

Quality Control

Our 9,11-Dioxo-15S-Hydroxy-Prosta-5Z,13E-Dien-1-Oic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be aligned with client requirements for advanced pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.