Description

3-Dimethylamino-Propane-1-Sulfonyl Chloride is a versatile sulfonyl chloride derivative, a key building block in organic synthesis. Its primary value lies in its dual functionality, acting as a reactive sulfonylation agent and a precursor for introducing the dimethylaminopropylsulfonyl moiety. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and advanced intermediates. Its reactivity profile makes it a critical component for developing sulfonamide-based compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that incorporate sulfonyl functional groups.
• Peptide Modification: Employed as a sulfonylation reagent for modifying amino acid side chains in peptide chemistry and bioconjugation.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating functional polymers with specific surface properties.
• Material Science: Used in the synthesis of specialty chemicals, dyes, and photoactive materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	3-Dimethylamino-Propane-1-Sulfonyl Chloride
CAS No.	273380-48-6
Molecular Formula	C5H12ClNO2S
Molecular Weight	185.67 g/mol
Synonyms	3-(Dimethylamino)propane-1-sulfonyl chloride; 3-(Dimethylamino)-1-propanesulfonyl chloride; N,N-Dimethyl-3-aminopropanesulfonyl chloride; 3-Dimethylaminopropanesulfonyl chloride; DMAPS-Cl; (3-Dimethylaminopropyl)sulfonyl chloride; 3-(N,N-Dimethylamino)propylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Dimethylamino-Propane-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with full batch traceability are provided. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.