Description

4-Ethylpiperazine-1-Sulfonyl Chloride (Hydrochloride Salt) is a high-purity sulfonyl chloride derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile reagent for introducing the sulfonamide functional group, a key motif in active pharmaceutical ingredients and advanced materials. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new sulfonamide-based compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing sulfonamide groups, particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfonamide moiety contributes to biological activity.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling, cross-linking, or modifying biomolecules in research applications.
• Polymer & Material Science: Employed as a monomer or cross-linking agent to create functional polymers with specific surface properties or reactivity.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in early-stage drug discovery programs.

Basic Information

Item	Details
Product Name	4-Ethylpiperazine-1-Sulfonyl Chloride (Hydrochloride Salt)
CAS No.	273207-02-6
Molecular Formula	C6H13ClN2O2S • HCl
Molecular Weight	249.16 g/mol (Free base: 212.70 g/mol)
Synonyms	1-(Ethylpiperazine)-4-sulfonyl chloride hydrochloride; 4-Ethylpiperazine-1-sulfonyl chloride HCl; N-Ethylpiperazine-1-sulfonyl chloride hydrochloride; 1-(Ethyl)piperazine-4-sulfonyl chloride hydrochloride; 4-Ethyl-1-piperazinesulfonyl chloride hydrochloride; Piperazine, 1-(ethyl)-, 4-sulfonyl chloride, hydrochloride; 273207-02-6 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Ethylpiperazine-1-Sulfonyl Chloride Hydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.