Description

tert-Butyl [3-(Chlorosulfonyl)Phenyl]Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its reactive chlorosulfonyl and protected amine functional groups. This compound is critical for the synthesis of complex molecules, offering a versatile building block for constructing sulfonamide and carbamate linkages under controlled conditions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those containing sulfonamide pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the sulfonyl chloride moiety is essential for activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules via selective reactions of the chlorosulfonyl and carbamate groups.
• Protease Inhibitor Development: Serves as a precursor in the synthesis of protease inhibitors, leveraging its ability to form stable sulfonamide bonds with target enzymes.
• Material Science Research: Investigated for the preparation of specialized polymers and functional materials that incorporate sulfonamide units.

Basic Information

Product Name	tert-Butyl [3-(Chlorosulfonyl)Phenyl]Carbamate
CAS No.	269747-26-4
Molecular Formula	C11H14ClNO4S
Molecular Weight	291.75 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]benzenesulfonyl chloride; 1-(tert-Butoxycarbonylamino)-3-chlorosulfonylbenzene; tert-Butyl (3-chlorosulfonylphenyl)carbamate; Boc-3-aminobenzenesulfonyl chloride; N-Boc-3-aminobenzenesulfonyl chloride; 3-(Boc-amino)benzenesulfonyl chloride; (3-Chlorosulfonylphenyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl [3-(Chlorosulfonyl)Phenyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.