Description

tert-Butyl [4-(Chlorosulfonyl)Phenyl]Carbamate is a high-purity, versatile chemical intermediate characterized by its reactive chlorosulfonyl and protected amine functional groups. This compound is critically important for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sulfonamide-based active ingredients and other advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfonamide moieties for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the sulfonyl chloride group enables further derivatization.
• Peptide Modification & Bioconjugation: Serves as a reagent for introducing sulfonamide linkages or protecting groups into peptides and other biomolecules.
• Material Science Research: Employed in the creation of specialty polymers, dyes, and functional materials that require specific sulfonamide or carbamate linkages.
• Chemical Biology Probes: Acts as a building block for developing molecular probes and inhibitors used in biochemical and cellular studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.

Basic Information

Product Name	tert-Butyl [4-(Chlorosulfonyl)Phenyl]Carbamate
CAS No.	269747-25-3
Molecular Formula	C11H14ClNO4S
Molecular Weight	291.75 g/mol
Synonyms	BOC-4-(Chlorosulfonyl)aniline; tert-Butyl N-[4-(Chlorosulfonyl)phenyl]carbamate; 4-[(tert-Butoxycarbonyl)amino]benzenesulfonyl chloride; 4-(BOC-amino)benzenesulfonyl chloride; N-BOC-4-aminobenzenesulfonyl chloride; 1-(tert-Butoxycarbonyl)-4-(chlorosulfonyl)benzene; BOC-ABS-Cl; 4-(N-Boc-amino)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our tert-Butyl [4-(Chlorosulfonyl)Phenyl]Carbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current industry best practices, and specifications can be aligned with client requirements for specific projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.