Description

Daidzein 4’-β-D-Glucuronide is a specific, high-purity glucuronide metabolite of the soy isoflavone daidzein. This compound is of significant interest as a critical reference standard and active pharmaceutical ingredient (API) intermediate for pharmacokinetic and metabolic studies. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories focused on nutraceutical, metabolic, and hormonal health research. The product, identified by CAS NO 264236-77-3, is supplied under stringent quality control to ensure reliability for sensitive applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification of daidzein metabolites in biological matrices via HPLC, LC-MS, or GC-MS.
• Metabolite Research: Essential for in vitro and in vivo studies investigating the absorption, distribution, metabolism, and excretion (ADME) of daidzein and related isoflavones.
• Nutraceutical & Dietary Supplement Analysis: Serves as a calibration standard for quality control and potency verification in isoflavone-based supplement formulations.
• Biochemical Reagent: Employed in enzymatic assays and studies involving glucuronidation pathways and phase II metabolism.
• Academic & Contract Research: A key material for universities and CROs conducting research on phytoestrogens, menopause, bone health, and cardiovascular benefits.
• API Intermediate: Used in the synthesis of more complex conjugated molecules for pharmaceutical development targeting estrogen-related conditions.

Basic Information

Item	Detail
Product Name	Daidzein 4’-β-D-Glucuronide
CAS No.	264236-77-3
Molecular Formula	C21H18O10
Molecular Weight	430.36 g/mol
Synonyms	Daidzein 4'-O-β-D-Glucuronide; Daidzein-4'-glucuronide; 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 4'-β-D-Glucopyranosiduronic Acid; 4'-Glucuronyl daidzein; Daidzein 4'-glucuronide sodium salt (related form); Daidzein 4'-O-glucuronide; 4'-O-β-D-Glucuronosyl daidzein
EINECS	Contact for details

Quality Control

Every batch of Daidzein 4’-β-D-Glucuronide is produced and analyzed under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and MS. Our quality commitment ensures the material is suitable for use as a high-grade reference standard in regulated research environments. Specifications can be aligned with customer-specific requirements for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment. For long-term storage, consider desiccants and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.