Description

n-Hydroxy-4-[5-(Trifluoromethyl)pyridin-2-yl]oxybenzenecarboximidamide is a high-value, specialized organic intermediate featuring a unique trifluoromethylpyridine and hydroxyamidine pharmacophore. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group enhances metabolic stability and bioavailability. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop new products with optimized properties.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of potential drug candidates, particularly in areas like kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme mechanisms and biological pathways due to its metal-chelating hydroxyamidine moiety.
• Material Science: Can be incorporated into the synthesis of specialty polymers and ligands for catalysis, leveraging its aromatic and coordinating functionalities.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	n-Hydroxy-4-[5-(Trifluoromethyl)pyridin-2-yl]oxybenzenecarboximidamide
CAS No.	263161-34-8
Molecular Formula	C13H10F3N3O2
Molecular Weight	297.24 g/mol
Synonyms	4-[[5-(Trifluoromethyl)-2-pyridinyl]oxy]-N-hydroxybenzenecarboximidamide; 4-((5-(Trifluoromethyl)pyridin-2-yl)oxy)benzohydroxamidine; Benzenecarboximidamide, N-hydroxy-4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]-; 263161-34-8; 4-[(5-Trifluoromethylpyridin-2-yl)oxy]benzamidoxime; N-Hydroxy-4-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzamidine
EINECS	Contact for details

Quality Control

Our n-Hydroxy-4-[5-(Trifluoromethyl)pyridin-2-yl]oxybenzenecarboximidamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature of being easily oxidized, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.