Description

2-Bromo-5-Methylbenzotrifluoride is a versatile halogenated aromatic building block characterized by its bromine and trifluoromethyl substituents. This compound is valued for its role as a key intermediate in advanced organic synthesis, enabling the introduction of functionalized aromatic systems. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzotrifluoride scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed reactions such as Suzuki, Stille, or Buchwald-Hartwig aminations for constructing complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Bromo-5-Methylbenzotrifluoride
CAS No.	261952-20-9
Molecular Formula	C8H6BrF3
Molecular Weight	239.04 g/mol
Synonyms	1-Bromo-2-methyl-4-(trifluoromethyl)benzene; 2-Methyl-5-(trifluoromethyl)bromobenzene; α,α,α-Trifluoro-2-bromo-5-methyltoluene; 2-Bromo-α,α,α-trifluoro-5-xylene; 2-Bromo-5-methyl-α,α,α-trifluorotoluene; 4-(Trifluoromethyl)-2-bromotoluene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methylbenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC/HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.