Description

4-Methyl-3-(trifluoromethyl)benzyl bromide is a versatile and high-value organobromide building block, essential for advanced synthetic chemistry. Its molecular structure, featuring both a reactive benzyl bromide group and a trifluoromethyl substituent, makes it a critical intermediate for introducing lipophilic and electron-withdrawing properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport materials and host compounds for OLED devices.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create complex biaryl structures.
• Material Science Research: Used to incorporate fluorinated aromatic units into polymers and advanced organic materials to modify physical properties.

Basic Information

Item	Details
Product Name	4-Methyl-3-(trifluoromethyl)benzyl Bromide
CAS No.	261952-19-6
Molecular Formula	C9H8BrF3
Molecular Weight	253.06 g/mol
Synonyms	α-Bromo-4-methyl-α,α,α-trifluoro-m-xylene; 1-(Bromomethyl)-4-methyl-2-(trifluoromethyl)benzene; 3-(Trifluoromethyl)-4-methylbenzyl Bromide; (4-Methyl-3-(trifluoromethyl)phenyl)methyl Bromide; m-Xylene, α-bromo-4-methyl-α,α,α-trifluoro-; 2-(Trifluoromethyl)-4-methylbenzyl Bromide
EINECS	Contact for details

Quality Control

Every batch of 4-Methyl-3-(trifluoromethyl)benzyl bromide is produced under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure product identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.