Description

2-Methyl-5-(Trifluoromethyl)Benzyl Bromide is a versatile and high-value benzyl bromide derivative, distinguished by the presence of a trifluoromethyl group which imparts unique physicochemical properties. This compound serves as a critical alkylating agent and synthetic building block in advanced organic synthesis, enabling the introduction of a substituted benzyl moiety. It is primarily utilized by pharmaceutical, agrochemical, and advanced material research sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring lipophilic and electron-withdrawing substituents.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Used in the preparation of fluorinated aromatic cores for electronic and photonic materials.
• Cross-Coupling Reactions: Serves as an electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to create complex biaryl structures.
• Functional Polymer Modification: Agent for introducing benzyl groups into polymer backbones to alter solubility, thermal stability, or other material properties.
• Chemical Biology & Proteomics: Potential use as a labeling or affinity probe due to its reactive benzyl bromide handle.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Benzyl Bromide
CAS No.	261952-17-4
Molecular Formula	C9H8BrF3
Molecular Weight	253.06 g/mol
Synonyms	α-Bromo-2-methyl-5-(trifluoromethyl)toluene; 1-(Bromomethyl)-2-methyl-5-(trifluoromethyl)benzene; (2-Methyl-5-(trifluoromethyl)phenyl)methyl bromide; 5-(Trifluoromethyl)-2-methylbenzyl bromide; 2-Methyl-α,α,α-trifluoro-m-tolyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-5-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality management systems. Our products undergo rigorous quality testing including HPLC, GC, and NMR analysis to ensure compliance with stringent purity specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.