Description

2-Bromo-5-(Trifluoromethoxy)Toluene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethoxy substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethoxy and bromoaryl motifs for bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the introduced functional groups enhance product efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a building block for advanced electronic materials, where its aromatic core and halogen/fluorine substituents help fine-tune electronic properties and molecular alignment.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form complex biaryl structures.
• Functional Polymer Monomer: Employed in the research and development of specialty polymers with specific optical, electronic, or surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Bromo-5-(Trifluoromethoxy)Toluene
CAS No.	261951-96-6
Molecular Formula	C9H6BrF3O
Molecular Weight	255.04 g/mol
Synonyms	1-Bromo-2-methyl-4-(trifluoromethoxy)benzene; 2-Methyl-5-(trifluoromethoxy)bromobenzene; 4-(Trifluoromethoxy)-2-bromotoluene; 2-Bromo-5-(trifluoromethoxy)-1-methylbenzene; α,α,α-Trifluoro-2-bromo-5-cresyl methyl ether; Toluene, 2-bromo-5-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Trifluoromethoxy)Toluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 2°C and 25°C. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.