Description

4-Methoxy-3-(trifluoromethyl)benzyl bromide is a versatile and high-value benzyl bromide derivative, distinguished by the presence of both methoxy and trifluoromethyl functional groups. This compound serves as a critical alkylating agent and synthetic building block in advanced organic synthesis, enabling the introduction of a functionalized benzyl moiety. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical research and development teams for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced functional materials used in electronic displays and optoelectronic devices.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and molecular recognition applications.
• Custom Chemical Synthesis: A valuable reagent for contract research organizations (CROs) and custom synthesis laboratories for producing tailored fine chemicals.
• Fluorine Chemistry Research: Essential for academic and industrial research focused on incorporating fluorine atoms into organic molecules to modulate their properties.

Basic Information

Product Name	4-Methoxy-3-(Trifluoromethyl)Benzyl Bromide
CAS No.	261951-89-7
Molecular Formula	C9H8BrF3O
Molecular Weight	269.06 g/mol
Synonyms	1-(Bromomethyl)-4-methoxy-3-(trifluoromethyl)benzene; 3-(Trifluoromethyl)-4-methoxybenzyl Bromide; α-Bromo-4-methoxy-α,α,α-trifluoro-m-xylene; 4-Methoxy-α,α,α-trifluoro-m-tolylmethyl Bromide; (4-Methoxy-3-(trifluoromethyl)phenyl)methyl Bromide
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxy-3-(trifluoromethyl)benzyl bromide is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and compliance with your project specifications. Our quality commitment supports applications requiring GMP-grade intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.