Description

5-Fluoro-2-Methylbenzyl Bromide is a versatile and high-purity benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive benzylic halide site and a fluorine substituent, enabling precise molecular construction for complex target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorinated methylbenzyl motifs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalysis and molecular recognition.
• Material Science Research: Building block for fluorinated liquid crystals, polymers, and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Fluoro-2-Methylbenzyl Bromide
CAS No.	261951-71-7
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	1-(Bromomethyl)-5-fluoro-2-methylbenzene; (5-Fluoro-2-methylphenyl)methyl Bromide; α-Bromo-5-fluoro-2-methyltoluene; 2-Methyl-5-fluorobenzyl Bromide; 5-Fluoro-o-tolylmethyl Bromide; 5-Fluoro-2-methylbenzylbromide; 5-Fluoro-2-methyl-benzylbromide
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-2-Methylbenzyl Bromide is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.