Description

5-Bromo-2,4-difluorobenzotrifluoride is a high-value fluorinated aromatic building block characterized by its bromine and fluorine substituents, which enable versatile functionalization. This compound is essential for introducing the benzotrifluoride moiety into complex molecular architectures, a key strategy in modern agrochemical and pharmaceutical design. It is primarily sought by R&D chemists and process engineers in the life sciences sector for the synthesis of advanced intermediates, active ingredients, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring the metabolically stable and lipophilic benzotrifluoride group.
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and insecticides where the difluorobenzotrifluoride core enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Functional Material Modifier: Incorporated to impart specific properties like chemical resistance, thermal stability, or altered surface energy in advanced polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to create more complex biaryl structures.
• Research & Development: A valuable tool for medicinal chemistry and material science research in exploring new chemical entities and property-activity relationships.

Basic Information

Product Name	5-Bromo-2,4-difluorobenzotrifluoride
CAS No.	261945-71-5
Molecular Formula	C7H2BrF5
Molecular Weight	260.99 g/mol
Synonyms	2,4-Difluoro-5-bromobenzotrifluoride; 1-Bromo-2,4-difluoro-5-(trifluoromethyl)benzene; 5-Bromo-α,α,α,2,4-pentafluorotoluene; Benzene, 1-bromo-2,4-difluoro-5-(trifluoromethyl)-; 5-Bromo-2,4-difluoro-α,α,α-trifluorotoluene; 2,4-Difluoro-5-bromo-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,4-difluorobenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC/HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specification results are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.