Description

3,5-Difluorobenzylmethylsulfone is a high-purity fluorinated organic sulfone building block of significant importance in advanced chemical synthesis. Its unique structure, featuring a difluorinated benzyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or modifier in the development of specialty polymers, liquid crystals, and electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a versatile scaffold for constructing complex heterocycles and sulfone-containing compounds in medicinal chemistry.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and structure-activity relationships (SAR).

Basic Information

Item	Details
Product Name	3,5-Difluorobenzylmethylsulfone
CAS No.	261924-28-1
Molecular Formula	C8H8F2O2S
Molecular Weight	206.21 g/mol
Synonyms	1-(Methylsulfonyl)methyl-3,5-difluorobenzene; (3,5-Difluorophenyl)methyl methyl sulfone; 3,5-Difluoro-α-(methylsulfonyl)toluene; 3,5-Difluorobenzyl Methyl Sulfone; Methyl (3,5-difluorobenzyl) sulfone; 3,5-Difluorobenzylmethanesulfonate (common misnomer); 3,5-DFBMS
EINECS	Contact for details

Quality Control

Our 3,5-Difluorobenzylmethylsulfone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring stringent material consistency, from early-stage research to scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.