Description

2,6-Difluoro-3-Methylbenzyl Bromide is a high-value fluorinated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring fluorine atoms and a reactive bromomethyl group, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl moiety can enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals, where fluorine incorporation modifies thermal stability and optical properties.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2,6-Difluoro-3-Methylbenzyl Bromide
CAS No.	261763-44-4
Molecular Formula	C8H7BrF2
Molecular Weight	221.04 g/mol
Synonyms	1-(Bromomethyl)-2,6-difluoro-3-methylbenzene; (2,6-Difluoro-3-methylphenyl)methyl bromide; 3-Methyl-2,6-difluorobenzyl bromide; α-Bromo-2,6-difluoro-3-methyltoluene; 2,6-Difluoro-3-methyl-benzylbromide; Benzene, 1-(bromomethyl)-2,6-difluoro-3-methyl-; 261763-44-4
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-3-Methylbenzyl Bromide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.