Description

2-Chloro-3-(Trifluoromethyl)Benzyl Bromide is a high-value halogenated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it an essential reagent for introducing functionalized benzyl groups into target molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzyl moiety.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized monomers or additives for advanced polymers and liquid crystals.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Fluorine Chemistry: A valuable substrate for further functionalization in fluorochemical research, leveraging the reactive benzyl bromide and trifluoromethyl groups.

Basic Information

Product Name	2-Chloro-3-(Trifluoromethyl)Benzyl Bromide
CAS No.	261763-22-8
Molecular Formula	C8H5BrClF3
Molecular Weight	273.48 g/mol
Synonyms	1-(Bromomethyl)-2-chloro-3-(trifluoromethyl)benzene; α-Bromo-2-chloro-α,α,α-trifluoro-o-xylene; (2-Chloro-3-(trifluoromethyl)phenyl)methyl bromide; 2-Chloro-α-(bromomethyl)-3-(trifluoromethyl)toluene; o-Chloro-α-bromomethyl-α,α,α-trifluorotoluene; Benzyl bromide, 2-chloro-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive analytical data including HPLC for purity and identity confirmation via NMR and IR. Certificates of Analysis (COA) detailing all specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its light-sensitive nature and reactive benzyl bromide group, it is recommended to handle under an inert atmosphere for extended storage and use appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.