Description

4-Methyl-6-Trifluoromethyl-Nicotinic Acid is a high-value, multi-functional heterocyclic building block characterized by its nicotinic acid core substituted with methyl and trifluoromethyl groups. This compound is prized for its role as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial R&D.

Basic Information

Product Name	4-Methyl-6-Trifluoromethyl-Nicotinic Acid
CAS No.	261635-74-9
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	6-(Trifluoromethyl)-4-methylpyridine-3-carboxylic acid; 4-Methyl-6-(trifluoromethyl)nicotinic acid; 3-Pyridinecarboxylic acid, 4-methyl-6-(trifluoromethyl)-; 4-Methyl-6-trifluoromethylnicotinic acid; 4-Methyl-6-trifluoromethyl-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Methyl-6-Trifluoromethyl-Nicotinic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.