Description

Hypertensin is a synthetic peptide compound, also known as Angiotensin II, which plays a critical role in the regulation of blood pressure and fluid balance. This high-purity compound is essential for advanced biochemical research and pharmaceutical development, particularly in cardiovascular studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers for applications in receptor binding assays, hypertension research, and as a reference standard.

Application

• Biochemical Research: Used as a key agonist for studying the renin-angiotensin system (RAS) and its role in cardiovascular physiology and pathology.
• Pharmaceutical Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) in the development of antihypertensive drugs and angiotensin receptor blockers (ARBs).
• Diagnostic Reagents: Employed in the formulation of in-vitro diagnostic kits for measuring renin activity and related biomarkers.
• Cell Signaling Studies: Applied in cell culture and tissue experiments to investigate G-protein coupled receptor (GPCR) signaling pathways.
• Vasoconstriction Assays: Utilized in ex-vivo and in-vitro models to study vascular tone and endothelial function.

Basic Information

Product Name	Hypertensin
CAS No.	260961-67-9
Molecular Formula	C50H71N13O12
Molecular Weight	1046.2 g/mol
Synonyms	Angiotensin II; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe; DRVYIHPF; All-Des-Asp1-Angiotensin I; Angiotensin II (human); [Asn1, Val5]-Angiotensin II; Hypertensin II; Angiotensinamide
EINECS	Contact for details

Quality Control

Our Hypertensin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and stringent tests for residual solvents and related substances. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.