Description

2-Chloromethyl-3,5-Dimethyl-4-Trifluoroethyl Pyridine is a versatile and highly functionalized pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique combination of reactive chloromethyl and trifluoroethyl groups on the pyridine ring, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries who require high-purity building blocks for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoroethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized pyridine-based ligands used in transition metal catalysis for fine chemical manufacturing.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	2-Chloromethyl-3,5-Dimethyl-4-Trifluoroethyl Pyridine
CAS No.	256642-27-0
Molecular Formula	C11H13ClF3N
Molecular Weight	251.67 g/mol
Synonyms	4-(2,2,2-Trifluoroethyl)-3,5-dimethyl-2-pyridinemethanol chloride; 2-(Chloromethyl)-3,5-dimethyl-4-(2,2,2-trifluoroethyl)pyridine; 3,5-Dimethyl-4-(2,2,2-trifluoroethyl)-2-pyridinemethyl chloride; 2-Pyridinemethanol, 4-(2,2,2-trifluoroethyl)-3,5-dimethyl-, chloride; 256642-27-0; 4-Trifluoroethyl-3,5-dimethyl-2-chloromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Chloromethyl-3,5-Dimethyl-4-Trifluoroethyl Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of advanced intermediate applications. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.