Description

5-Fluoroisophthalaldehyde is a versatile fluorinated aromatic dialdehyde building block. This compound is highly valued in advanced organic synthesis for its two reactive aldehyde groups and the electron-withdrawing fluorine substituent, which enables precise molecular construction. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel heterocycles, ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex heterocyclic scaffolds and fluorinated drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Chelator Preparation: Serves as a starting material for synthesizing sophisticated Schiff base ligands, macrocycles, and chelating agents used in catalysis and metal ion sequestration.
• Polymer and Material Science: Employed as a monomer or cross-linking agent in the production of specialty polymers, resins, and porous organic frameworks (e.g., COFs, MOFs).
• Chemical Research & Development: A fundamental building block in academic and industrial R&D for exploring new fluorinated organic compounds and reaction methodologies.
• Dye and Pigment Intermediate: Utilized in the synthesis of fluorinated dyes and functional pigments with tailored optical properties.

Basic Information

Product Name	5-Fluoroisophthalaldehyde
CAS No.	255375-90-7
Molecular Formula	C8H5FO2
Molecular Weight	152.12 g/mol
Synonyms	5-Fluorobenzene-1,3-dicarbaldehyde; 1,3-Benzenedicarboxaldehyde, 5-fluoro-; Isophthalaldehyde, 5-fluoro-; 5-Fluoroisophthalic dialdehyde; 3-Formyl-5-fluorobenzaldehyde; 5-Fluoro-1,3-benzenedicarboxaldehyde; 5-Fluorobenzene-1,3-dialdehyde
EINECS	Contact for details

Quality Control

Our 5-Fluoroisophthalaldehyde is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.