Description

2-Propen-1-One, 2-(1H-Benzimidazol-1-Yl)-1-(2,4-Dichlorophenyl)-3-(Dimethylamino)- is a high-purity, functionalized benzimidazole derivative with a complex α,β-unsaturated ketone (enone) structure. This compound is valued as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the development of novel bioactive molecules. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting infectious diseases or cancer, leveraging the benzimidazole pharmacophore.
• Agrochemical Research: Used in developing novel fungicides or pesticides, where the dichlorophenyl and benzimidazole moieties can contribute to pesticidal activity.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex heterocyclic systems via reactions at its enone and amine functional groups.
• Material Science Precursor: Investigated for the synthesis of specialized polymers or ligands for metal-organic frameworks (MOFs) due to its multifunctional structure.

Basic Information

Product Name	2-Propen-1-One, 2-(1H-Benzimidazol-1-Yl)-1-(2,4-Dichlorophenyl)-3-(Dimethylamino)-
CAS No.	252954-63-5
Molecular Formula	C18H15Cl2N3O
Molecular Weight	360.24 g/mol
Synonyms	1-(2,4-Dichlorophenyl)-3-(dimethylamino)-2-(1H-benzimidazol-1-yl)-2-propen-1-one; 2-(1H-Benzimidazol-1-yl)-1-(2,4-dichlorophenyl)-3-(dimethylamino)-2-propen-1-one; 3-(Dimethylamino)-1-(2,4-dichlorophenyl)-2-(1H-benzimidazol-1-yl)-2-propen-1-one; (2E)-2-(1H-Benzimidazol-1-yl)-1-(2,4-dichlorophenyl)-3-(dimethylamino)-2-propen-1-one; CAS 252954-63-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all specified parameters. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.