Description

2-Chloro-4,5-Difluorotoluene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials who require reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those containing difluoromethyl and chlorophenyl motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic display and lighting applications.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitution to introduce functionalized toluene derivatives.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new synthetic pathways and creating specialized chemical libraries.
• Polymer Modification: Acts as a monomer or modifier in the synthesis of specialty polymers with enhanced properties.

Basic Information

Product Name	2-Chloro-4,5-Difluorotoluene
CAS No.	252936-45-1
Molecular Formula	C7H5ClF2
Molecular Weight	162.56 g/mol
Synonyms	1-Chloro-2,3-difluoro-4-methylbenzene; 2,3-Difluoro-4-methylchlorobenzene; 4-Methyl-2,3-difluorochlorobenzene; Toluene, 2-chloro-4,5-difluoro-; 2-Chloro-4,5-difluoro-1-methylbenzene; 2-Chloro-4,5-difluoromethylbenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-4,5-Difluorotoluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.3 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.