Description

5-tert-Butyl-2-Ethoxybenzene-1-Sulfonyl Chloride is a specialized organic intermediate featuring a sulfonyl chloride functional group, making it a highly reactive and versatile building block for chemical synthesis. Its primary value lies in its ability to act as a sulfonylation agent, enabling the introduction of the sulfonyl moiety into target molecules, which is critical for modifying physicochemical properties and biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those requiring sulfonamide or sulfonate ester linkages for enhanced bioavailability or target binding.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the sulfonyl group contributes to efficacy and environmental stability.
• Material Science Research: Employed in the development of specialty polymers, dyes, and photoinitiators where the introduction of sulfonyl groups can alter material properties like solubility and thermal stability.
• Chemical Derivatization: Serves as a reagent for analytical chemistry, used to derivative compounds for detection or separation purposes in chromatographic methods.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical and custom synthesis houses producing bespoke molecules for client R&D and scale-up projects.

Basic Information

Product Name	5-tert-Butyl-2-Ethoxybenzene-1-Sulfonyl Chloride
CAS No.	252898-57-0
Molecular Formula	C₁₂H₁₇ClO₃S
Molecular Weight	276.78 g/mol
Synonyms	2-Ethoxy-5-tert-butylbenzenesulfonyl chloride; 5-tert-Butyl-2-ethoxybenzenesulfonyl chloride; 1-(tert-Butyl)-4-ethoxy-2-sulfonylchloridobenzene; 4-tert-Butyl-1-ethoxy-2-sulfonyl chloride benzene; 2-tert-Butyl-5-ethoxybenzenesulfonyl chloride; p-tert-Butyl-o-ethoxybenzenesulfonyl chloride; Benzenesulfonyl chloride, 5-(1,1-dimethylethyl)-2-ethoxy-
EINECS	Contact for details

Quality Control

Our production of 5-tert-Butyl-2-Ethoxybenzene-1-Sulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure consistency and reliability. A Certificate of Analysis (COA) detailing all critical parameters is provided with each shipment. We support compliance with global regulatory frameworks, and our quality system is designed to meet the exacting standards of pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.