Description

2-Pyridin-4-Ylethanesulfonyl Chloride is a versatile and reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group to create novel compounds with targeted properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with enhanced efficacy.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling, modifying, or cross-linking biomolecules in research applications.
• Material Science: Employed in the creation of specialty polymers and functional materials requiring specific sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	2-Pyridin-4-Ylethanesulfonyl Chloride
CAS No.	252670-82-9
Molecular Formula	C7H8ClNO2S
Molecular Weight	205.66 g/mol
Synonyms	4-(2-Chloroethanesulfonyl)pyridine; 2-(Pyridin-4-yl)ethanesulfonyl chloride; 4-(2-Chloroethylsulfonyl)pyridine; 2-(4-Pyridyl)ethanesulfonyl chloride; 4-Pyridineethanesulfonyl chloride; 2-(4-Pyridinyl)ethanesulfonyl chloride; (4-Pyridin-2-ylethyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Pyridin-4-Ylethanesulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.