Description

1-Bromo-2,5-Difluoro-4-Methylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing difluorophenyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides.
• Liquid Crystal & OLED Materials: Serves as a precursor for the development of fluorinated organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Material Research: Employed in the creation of novel polymers, ligands, and specialty chemicals with tailored properties.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries in medicinal chemistry.

Basic Information

Product Name	1-Bromo-2,5-Difluoro-4-Methylbenzene
CAS No.	252004-42-5
Molecular Formula	C7H5BrF2
Molecular Weight	207.02 g/mol
Synonyms	2,5-Difluoro-4-methylbromobenzene; 4-Bromo-2,5-difluorotoluene; 1-Bromo-2,5-difluoro-4-methyl-benzene; 2,5-Difluoro-4-methylphenyl bromide; (2,5-Difluoro-4-methylphenyl)bromide; Toluene, 4-bromo-2,5-difluoro-; Benzene, 1-bromo-2,5-difluoro-4-methyl-
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,5-Difluoro-4-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Purity (GC/HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.