Description

3-Fluoro-2-Iodo-Quinoline-4-Carbaldehyde is a high-value, multi-functional halogenated quinoline derivative. This compound serves as a critical synthetic intermediate, prized for its reactive aldehyde and halogen substituents which enable diverse chemical transformations. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic scaffolds and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Research: Used in developing advanced fungicides and herbicides due to its bioactive quinoline core.
• Material Science Precursor: Serves as a starting material for creating functionalized organic ligands and metal-organic frameworks (MOFs).
• Chemical Synthesis: Enables Suzuki-Miyaura and other cross-coupling reactions via the iodine moiety, and serves as an electrophile via the aldehyde group.
• Academic & Contract Research: Essential reagent for methodological development and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name	3-Fluoro-2-Iodo-Quinoline-4-Carbaldehyde
CAS No.	250739-98-1
Molecular Formula	C10H5FINO
Molecular Weight	317.06 g/mol
Synonyms	2-Iodo-3-fluoroquinoline-4-carboxaldehyde; 4-Quinolinecarboxaldehyde, 3-fluoro-2-iodo-; 3-Fluoro-2-iodoquinoline-4-carbaldehyde; 3-Fluoro-2-iodo-4-quinolinecarbaldehyde; 250739-98-1; 2-Iodo-3-fluoro-4-quinolinecarboxaldehyde; 3-Fluoro-2-iodo-4-formylquinoline
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Iodo-Quinoline-4-Carbaldehyde is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure high consistency and reliability for your synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.