Description

1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanone is a high-purity, versatile trifluoromethylated pyridine derivative, serving as a critical building block in advanced chemical synthesis. Its value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl group, enabling the development of novel compounds with enhanced stability and biological activity. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the CF3 group improves lipophilicity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of advanced organic materials, including liquid crystals and electronic chemicals.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry and process R&D for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals for client projects.

Basic Information

Item	Detail
Product Name	1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanone
CAS No.	248274-16-0
Molecular Formula	C8H6F3NO
Molecular Weight	189.14 g/mol
Synonyms	2-Acetyl-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-acetylpyridine; 1-[5-(Trifluoromethyl)-2-pyridinyl]ethanone; 2-Pyridineethanone, 5-(trifluoromethyl)-; Ethanone, 1-[5-(trifluoromethyl)-2-pyridinyl]-
EINECS	Contact for details

Quality Control

Our 1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.