Description

4-Chloromethylperfluorotoluene is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique structure, which combines a reactive chloromethyl group with a highly fluorinated, electron-deficient aromatic core, enabling the introduction of perfluoroaryl motifs into complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel fluorinated compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for introducing perfluorotoluene-derived pharmacophores into potential drug candidates, particularly in medicinal chemistry programs targeting enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and development of novel fluorinated pesticides and herbicides, where the perfluoroaryl group can influence biological activity and environmental persistence.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic segments.
• Ligand and Catalyst Development: Employed to synthesize novel fluorinated ligands for catalysis, leveraging the electron-withdrawing nature of the perfluoroaryl group to modulate metal center reactivity.
• Surface Modification Agent: Utilized to create low-surface-energy, hydrophobic coatings on various substrates via chemical grafting of the perfluoroaryl moiety.
• Fluorinated Dye and Pigment Intermediate: Provides a core structure for developing new classes of fluorinated colorants with unique solubility and stability profiles.

Basic Information

Product Name	4-Chloromethylperfluorotoluene
CAS No.	248262-31-9
Molecular Formula	C8H2ClF7
Molecular Weight	266.54 g/mol
Synonyms	α,α,α,2,3,5,6-Heptafluoro-4-(chloromethyl)toluene; Perfluoro(4-chloromethyltoluene); 4-(Chloromethyl)-2,3,5,6-tetrafluoro-α,α,α-trifluorotoluene; 1-Chloromethyl-2,3,5,6-tetrafluoro-4-(trifluoromethyl)benzene; Heptafluoro-4-chloromethyltoluene; (Perfluorotolyl)methyl chloride; 4-(Chloromethyl)heptafluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Chloromethylperfluorotoluene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We are committed to supplying material that meets the exacting standards required for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.