Description

2-(5-(Trifluoromethyl)Pyridin-2-Yl)Acetic Acid Hydrochloride is a high-purity, synthetically valuable trifluoromethylpyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique combination of the pyridine scaffold and the electron-withdrawing trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and asymmetric synthesis.
• Material Science Research: Intermediate for creating functionalized polymers, liquid crystals, or organic electronic materials with tailored properties.
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes used in biochemical and pharmacological research.

Basic Information

Product Name	2-(5-(Trifluoromethyl)Pyridin-2-Yl)Acetic Acid Hydrochloride
CAS No.	247200-00-6
Molecular Formula	C8H7ClF3NO2
Molecular Weight	241.59 g/mol
Synonyms	[2-(5-Trifluoromethyl-2-pyridyl)acetyl] chloride hydrochloride; 2-[5-(Trifluoromethyl)-2-pyridinyl]acetic acid hydrochloride; 2-(5-Trifluoromethylpyridin-2-yl)acetic acid HCl; 5-(Trifluoromethyl)pyridine-2-acetic acid hydrochloride; α-(5-Trifluoromethyl-2-pyridyl)acetic acid hydrochloride; (5-Trifluoromethyl-2-pyridyl)acetic acid hydrochloride; 2-Pyridineacetic acid, 5-(trifluoromethyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-(5-(Trifluoromethyl)Pyridin-2-Yl)Acetic Acid Hydrochloride is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and scale-up. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.